Standing-wave Design of Three-Zone, open-loop non-isocratic SMB for purification

Table 2 Column and Simulation Parameters for Examples 1 and 2

System Parameters
L_C (cm)	Number of columns	Column Diameter (cm)	d_p (μm)	ε _b	ε _p	Y	\( {E}_{b,i}^j \)	Film Mass Transfer Coefficient
2.5	3	Exp. 1: 0.5	Exp. 1: 44	0.35	0.69	0.99	Chung and Wen	Wilson and Geankoplis
2.5	3	Exp. 2: 0.7	Exp. 2: 34	0.35	0.69	0.99	Chung and Wen	Wilson and Geankoplis
Isotherm Parameters
Example 1
Target Compound				Impurity
q _max	K _A	pH _ref	n	a ₁
73 g/L	6.1 L/g	7.4	16.6	1.6
Example 2
a _{o, i}		x _i		a _{o, i}			x _i
0.79		2.01		0.79			2.01
Simulation Settings and Numerical Parameters
PDE Discretization Method	Number of Elements	Material Balance Assumption			Kinetic Model Assumption		Lumped Resistance Film Mode
QDS	Exp. 1: 181	Convection with Estimated Dispersion			Linear Lumped Resistance		Exp. 1: Fluid
QDS	Exp. 2: 150	Convection with Estimated Dispersion			Linear Lumped Resistance		Exp. 2: Solid
Mass Transfer/Film Coefficient		Loading Basis	Step Size				Integration Method
Constant		Volume Basis	0.000005–0.005				Fixed Step Implicit Euler

ISSN: 2524-4175