Category | Type of variable | Number of parameters used in the case study |
---|---|---|
Internal variables determined at later stages | ||
Dosage unit size and composition | Continuous | 9 |
Number of PATs installed | Continuous | 2 |
Manufacturing space | Continuous | 2 |
Manufacturing rate in continuous technology | Continuous | 1 |
Time related to production, cleaning, and test | Continuous | 19 |
Losses | Continuous | 11 |
Number of operators | Discrete | 21 |
Number of lots in one campaign manufacturing | Discrete | 2 |
External variables given at later stages | ||
Raw material price | Continuous | 7 |
Demand/required amount | Discrete | 6 |
Man-hours of work in the maintenance of PAT per one PAT | Continuous | 1 |
Disposal/HVAC cost | Continuous | 2 |
Drug price | Continuous | 1 |
Success/failure of clinical development | Categorical | 1 |