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Table 6 Overview of the generated alternatives

From: Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing

Alternative numberCombination of the general units in Fig. 1TechnologyFormulation strategy
1\( {\mathrm{U}}_{10}^{\mathrm{C}} \), \( {\mathrm{U}}_{12}^{\mathrm{C}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{C}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{C}} \), U18ContinuousProportional
2\( {\mathrm{U}}_{10}^{\mathrm{C}} \), \( {\mathrm{U}}_{12}^{\mathrm{C}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{C}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{C}} \), U18ContinuousCommon
3\( {\mathrm{U}}_{10}^{\mathrm{B}} \), \( {\mathrm{U}}_{12}^{\mathrm{B}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{B}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{B}} \), U18Batch (high-shear)Proportional
4\( {\mathrm{U}}_{10}^{\mathrm{B}} \), \( {\mathrm{U}}_{12}^{\mathrm{B}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{B}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{B}} \), U18Batch (high-shear)Common
5\( {\mathrm{U}}_{11}^{\mathrm{B}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{B}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{B}} \), U18Batch (fluidized-bed)Proportional
6\( {\mathrm{U}}_{11}^{\mathrm{B}} \), U13, \( {\mathrm{U}}_{14}^{\mathrm{B}} \), U15, \( {\mathrm{U}}_{16}^{\mathrm{B}} \), U18Batch (fluidized-bed)Common