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Table 8 Values of the parameters varied in what-if analyses

From: Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing

 

Original value (left in Figs. 6 and 9)

Value used in what-if analysis

xstd

xmin

xmax

 

Scenario 1 (Fig. 6)

 Manufacturing rate in continuous technology v [kg h− 1]

25

10

25

19 (middle)

15 (right)

Scenario 2 (Fig. 9)

 Manufacturing rate in continuous technology v [kg h− 1]

25

10

25

25 (middle & right)

 Loss amount due to shut-down operation \( {m}_{\mathrm{loss},\mathrm{shut}}^{\mathrm{continuous}} \) [kg lot−1]

5.00

1.00

20.0

2.50 (right)

 Loss amount due to start-up operation \( {m}_{\mathrm{loss},\mathrm{start}}^{\mathrm{continuous}} \) [kg lot−1]

12.5

1.00

20.0

6.25 (right)