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Table 3 Design matrix of Box-Behnken Design data

From: Liquid-phase hydrogenation of bio-refined succinic acid to 1,4-butanediol using bimetallic catalysts

Run

Factor 1- A:Catalyst Concentration,%Ru-Co

Factor 2- B:Temperature, °C

Factor 3- C:Pressure, Bar

Response 1-

Yield of 1,4-BDO, %

1

1

250

60

0.41

2

1

180

60

0.26

3

2

180

75

3.44

4

3

250

60

5.01

5

2

215

60

3.64

6

2

250

75

3.67

7

2

250

45

3.91

8

2

215

60

4.69

9

2

180

45

3.66

10

2

215

60

4.09

11

2

215

60

4.03

12

3

215

45

4.38

13

2

215

60

4.01

14

3

215

75

5.03

15

1

215

75

0.63

16

3

180

60

4.63

17

1

215

45

0.39